In supplement form, Glucosamine plus is often combined with chondroitin sulfate, a molecule that is present in cartilage. It gives cartilage elasticity and is believed to help prevent the destruction of cartilage. These two combined leads to maximum absorption of the Glucosamine and a more effective treatment. When using Glucosamine complex, it is recommended that Chondroitin be taken at the same time. Most products now come with Chondroitin in the ingredients. Research on Glucosamine and Chondroitin has shown encouraging evidence that these supplements can provide help with treating osteoarthritis and cartilage degeneration problems. It has been found that glucosamine gel is the least effective.